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Deep learning quantified mucus-tumor ratio predicting survival of patients with colorectal cancer using whole-slide images

期刊: PRECISION CLINICAL MEDICINE, 2021; 4 (1)

Background: In colorectal cancer (CRC), mucinous adenocarcinoma differs from other adenocarcinomas in gene-phenotype, morphology, and prognosis. Howev......

Strategies for advanced personalized tuberculosis diagnosis: Current technologies and clinical approaches

期刊: PRECISION CLINICAL MEDICINE, 2021; 4 (1)

Diagnosis of tuberculosis can be difficult as advances in molecular diagnosis approaches (especially nanoparticles combined with high-throughput mass ......

Clinical longitudinal evaluation of COVID-19 patients and prediction of organ-specific recovery using artificial intelligence

期刊: PRECISION CLINICAL MEDICINE, 2021; 4 (1)

Within COVID-19 there is an urgent unmet need to predict at the time of hospital admission which COVID-19 patients will recover from the disease, and ......

Blood purification for sepsis: an overview

期刊: PRECISION CLINICAL MEDICINE, 2021; 4 (1)

Sepsis is a life-threatening organ failure exacerbated by a maladaptive infection response from the host, and is one of the major causes of mortality ......

JAM-A facilitates hair follicle regeneration in alopecia areata through functioning as ceRNA to protect VCAN expression in dermal papilla cells

期刊: PRECISION CLINICAL MEDICINE, 2022; 5 (3)

The dermal papilla cells in hair follicles function as critical regulators of hair growth. In particular, alopecia areata (AA) is closely related to t......

Patient-directed vs. fixed-volume PEG for colonoscopy preparation: a randomized controlled trial

期刊: PRECISION CLINICAL MEDICINE, 2022; 5 (2)

Background Individualization using different volumes of polyethylene glycol is widely regarded as the optimal solution for bowel preparation, while th......

A selective kernel-based cycle-consistent generative adversarial network for unpaired low-dose CT denoising

期刊: PRECISION CLINICAL MEDICINE, 2022; 5 (2)

Low-dose computed tomography (LDCT) denoising is an indispensable procedure in the medical imaging field, which not only improves image quality, but c......

Tumorigenicity risk of iPSCs in vivo: nip it in the bud

期刊: PRECISION CLINICAL MEDICINE, 2022; 5 (1)

In 2006, Takahashi and Yamanaka first created induced pluripotent stem cells from mouse fibroblasts via the retroviral introduction of genes encoding ......

Patient-derived organoids potentiate precision medicine in advanced clear cell renal cell carcinoma

期刊: PRECISION CLINICAL MEDICINE, 2022; 5 (4)

To investigate the role of patient-derived organoid (PDO) model in the precision medicine of advanced clear cell renal cell carcinoma (ccRCC), we retr......

A novel immunogenomic signature to predict prognosis and reveal immune infiltration characteristics in pancreatic ductal adenocarcinoma

期刊: PRECISION CLINICAL MEDICINE, 2022; 5 (2)

Background The immune response in the tumor microenvironment (TME) plays a crucial role in cancer progression and recurrence. We aimed to develop an i......

Infantile hepatic hemangiomas: looking backwards and forwards

期刊: PRECISION CLINICAL MEDICINE, 2022; 5 (1)

Infantile hepatic hemangiomas (IHHs) are common benign tumors seen in the liver of infants. IHHs are true infantile hemangiomas (IHs) and have phases ......

Inhibitory effect of lanosterol on cataractous lens of cynomolgus monkeys using a subconjunctival drug release system

期刊: PRECISION CLINICAL MEDICINE, 2022; 5 (3)

Background To evaluate the effect of lanosterol on cataractous lens of cynomolgus monkeys using a subconjunctival drug release system. Methods Nine el......

The latest breakthrough on NLRP6 inflammasome

期刊: PRECISION CLINICAL MEDICINE, 2022; 5 (3)

NLRP6, a Nod-like receptor family member, has been shown to affect intestinal homeostasis and microbial colonization through organizing a huge protein......

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