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Promotion of cadmium uptake and cadmium-induced toxicity by the copper transporter CTR1 in HepG2 and ZFL cells

期刊: TOXICOLOGY REPORTS, 2020; 7 ()

Cadmium (Cd2+) is considered a human carcinogen as it causes oxidative stress and alters DNA repair responses. However, how Cd2+ is taken up by cells ......

Comparative docking studies to understand the binding affinity of nicotine with soluble ACE2 (sACE2)-SARS-CoV-2 complex over sACE2

期刊: TOXICOLOGY REPORTS, 2020; 7 ()

The study aimed to validate the proficiency of nicotine binding with the soluble angiotensin-converting enzyme II receptor (sACE2) with or without SAR......

Assessment of carcinogenic and toxic substances in 'Insunko' herb

期刊: TOXICOLOGY REPORTS, 2020; 7 ()

There has emerged a herb in Zambia called 'insunko' which has unknown chemical composition. The use of 'insunko' herb with unknown chemical compositio......

Biodegradation of textile dye Reactive Blue 160 by Bacillus firmus (Bacillaceae: Bacillales) and non-target toxicity screening of their degraded products

期刊: TOXICOLOGY REPORTS, 2020; 7 ()

The study was envisioned to evaluate the decolorization of Reactive Blue 160 (RB160) dye by using indigenous microbes. Contaminated soil from textile ......

The impact of particulate matter (PM2.5) on skin barrier revealed by transcriptome analysis: Focusing on cholesterol metabolism

期刊: TOXICOLOGY REPORTS, 2020; 7 ()

Accumulating evidence suggests that particulate matter (PM2.5), as a major air pollutant, imposes a certain degree of destruction and toxicity to the ......

Welding fumes composition and their effects on blood heavy metals in albino rats

期刊: TOXICOLOGY REPORTS, 2020; 7 ()

Toxic substances produced during welding include heavy metals, carbon monoxide, carbon dioxide, and nitrogen oxides. The study aims to evaluate the he......

5-HMF induces anaphylactoid reactions in vivo and in vitro

期刊: TOXICOLOGY REPORTS, 2020; 7 ()

Aim: Excessive exposure to 5-hydroxymethylfurfural (5-HMF), which is a common impurity in various sugar-containing products, induces serious side effe......

Evaluation of acute and sub-chronic toxicity of lithothamnion sp. in mice and rats

期刊: TOXICOLOGY REPORTS, 2020; 7 ()

Lithothamnion sp., a red algae of the Corallinaceae family, when harvested in its calcareous form, is rich in calcium, magnesium and a variety of trac......

Oxidative stress and apoptotic e ff ects of copper and cadmium in the zebra fi sh liver cell line ZFL

期刊: TOXICOLOGY REPORTS, 2020; 7 ()

Copper (Cu) and cadmium (Cd) are widely used in industrial activities, resulting in Cu and Cd contamination in aquatic systems worldwide. Although Cu ......

Autophagy regulates the Wnt/GSK3 beta/beta-catenin/cyclin D1 pathway in mesenchymal stem cells (MSCs) exposed to titanium dioxide nanoparticles (TiO(2)NPs)

期刊: TOXICOLOGY REPORTS, 2020; 7 ()

The application of titanium dioxide nanoparticles (TiO(2)NPs) is on the increase, and so the number of studies dedicated to describing this material's......

Transient exposure to environmentally realistic concentrations of di-(2-ethylhexyl)-phthalate during sensitive windows of development impaired larval survival and reproduction success in Japanese medaka

期刊: TOXICOLOGY REPORTS, 2020; 7 ()

Di-(2-ethylhexyl) phthalate (DEHP) is a well-known endocrine disruptor and it is ubiquitously distributed in the environment. However, very few studie......

The characterization of a short chain dehydrogenase/reductase (SDRx) in Comamonas testosteroni

期刊: TOXICOLOGY REPORTS, 2020; 7 ()

C. testosteroni is a research topic that can degrade steroid hormones into water and carbon dioxide through a series of enzymes in the body. Short-cha......

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