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Polymorphisms in TYMS for Prediction of Capecitabine-Induced Hand-Foot Syndrome in Chinese Patients with Colorectal Cancer

Dong, SQ; Wang, TM; Zhang, JB; He, YQ; Xue, WQ; Wu, ZY; Yang, DW; Cao, LJ; Huang, JW; Li, XZ; Zhang, PF; Zheng, XH; Jia, WH

Jia, WH (corresponding author), Sun Yat Sen Univ, Guangdong Key Lab Nasopharyngeal Carcinoma Diag &, Collaborat Innovat Ctr Canc Med, State Key Lab Oncol South China,Canc Ctr, 651 Dongfeng East Rd,BLDG 2,RM903, Guangzhou 510060, Guangdong, Peoples R China.; Jia, WH (corresponding author), Sun Yat Sen Univ, Sch Publ Hlth, 651 Dongfeng East Rd,BLDG 2,RM903, Guangzhou 510060, Guangdong, Peoples R China.; Jia, WH (corresponding author), Sun Yat Sen Univ, Canc Ctr, Guangzhou Med Univ, 651 Dongfeng Ea

CANCER RESEARCH AND TREATMENT, 2021; 53 (3): 724

Abstract

Purpose Capecitabine is an extensively used oral prodrug of 5-fluorouracil in treatment of colon cancer and is known to cause hand foot syndrome (HFS)......

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