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IL-17 Facilitates VCAM-1 Production and Monocyte Adhesion in Osteoarthritis Synovial Fibroblasts by Suppressing miR-5701 Synthesis

Wu, TJ; Chang, SLY; Lin, CY; Lai, CY; He, XY; Tsai, CH; Ko, CY; Fong, YC; Su, CM; Tang, CH

Tang, CH (通讯作者),China Med Univ, Grad Inst Biomed Sci, Taichung 404333, Taiwan.;Tang, CH (通讯作者),Asia Univ, Dept Med Lab Sci & Biotechnol, Taichung 413305, Taiwan.;Su, CM (通讯作者),China Med Univ, Coll Hlth Care, Dept Sports Med, Taichung 406040, Taiwan.;Tang, CH (通讯作者),China Med Univ, Sch Med, Dept Pharmacol, Taichung 406040, Taiwan.;Tang, CH (通讯作者),China Med Univ, Chinese Med Res Ctr, Taichung 406040, Taiwan.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022; 23 (12):

Abstract

Osteoarthritis (OA) is characterized by the infiltration and adhesion of monocytes into the inflamed joint synovium. Interleukin (IL)-17 is a critical......

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