A polymeric nanoformulation improves the bioavailability and efficacy of sorafenib for hepatocellular carcinoma therapy-MedSci.cn

A polymeric nanoformulation improves the bioavailability and efficacy of sorafenib for hepatocellular carcinoma therapy

Chen, Y; Li, JX; Shu, N; Zheng, SJ; Ma, M; Zhao, ZB; Cao, ZT; Zhou, Q; Du, JZ; Wang, J

Du, JZ (corresponding author), South China Univ Technol, Guangzhou Peoples Hosp 1, Sch Med, Guangzhou 510006, Peoples R China.; Du, JZ (corresponding author), South China Univ Technol, Sch Med, Inst Life Sci, Guangzhou 510006, Peoples R China.; Du, JZ (corresponding author), South China Univ Technol, Natl Engn Res Ctr Tissue Restorat & Reconstruct, Key Lab Biomed Engn Guangdong Prov, Guangzhou 510006, Peoples R China.; Cao, ZT (corresponding author), China Pharmaceut Univ, Sch Biopharm, Nanjing

Abstract

Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death worldwide. Sorafenib (sfb) is widely used in clinics for advanced HCC therap......

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A polymeric nanoformulation improves the bioavailability and efficacy of sorafenib for hepatocellular carcinoma therapy

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