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Overexpressed PKM2 promotes macrophage phagocytosis and atherosclerosis

Gai, XC; Liu, FM; Wu, YT; Zhang, BH; Tang, BF; Shang, KZ; Wang, LM; Zhang, HH; Chen, YX; Yang, SH; Deng, WW; Li, P; Wang, J; Zhang, HB

Zhang, HB (通讯作者),Chinese Acad Med Sci & Peking Union Med Coll, State Key Lab Med Mol Biol, Dept Physiol, Inst Basic Med Sci, Beijing 100005, Peoples R China.;Wang, J; Zhang, HB (通讯作者),Chinese Acad Med Sci & Peking Union Med Coll, Sch Basic Med, Beijing 100005, Peoples R China.

ANIMAL MODELS AND EXPERIMENTAL MEDICINE, 2023; 6 (2): 92

Abstract

Background The expression of pyruvate kinase muscle 2 (PKM2) is augmented in macrophages of patients with atherosclerotic coronary artery disease. The......

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