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Inhibition of miR-146a-5p and miR-8114 in Insulin- Secreting Cells Contributes to the Protection of Melatonin against Stearic Acid-Induced Cellular Senescence by Targeting Mafa

Su, SH; Zhao, QR; Dan, LF; Lin, YQ; Li, XB; Zhang, YJ; Yang, CX; Dong, YM; Li, XH; Regazzi, R; Sun, CH; Chu, X; Lu, HM

Lu, HM (通讯作者),Harbin Med Univ, Publ Hlth Coll, Dept Nutr & Food Hyg, 157 Baojian Rd, Harbin 150081, Peoples R China.

ENDOCRINOLOGY AND METABOLISM, 2022; 37 (6): 901

Abstract

Background: Chronic exposure to elevated levels of saturated fatty acids results in pancreatic (3-cell senescence. However, targets and effective agen......

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