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NPTX2 and cognitive dysfunction in Alzheimers Disease

Xiao, MF; Xu, DS; Craig, MT; Pelkey, KA; Chien, CC; Shi, Y; Zhang, J; Resnick, S; Pletnikova, O; Salmon, D; Brewer, J; Edland, S; Wegiel, J; Tycko, B; Savonenko, A; Reeves, RH; Troncoso, JC; McBain, CJ; Galasko, D; Worley, PF

Worley, PF (reprint author), Johns Hopkins Univ, Sch Med, Solomon H Snyder Dept Neurosci, Baltimore, MD 21218 USA.; Worley, PF (reprint author), Johns Hopkins Univ Hosp, Sch Med, Dept Neurol, Baltimore, MD USA.

ELIFE, 2017; 6 ( ):

Abstract

Memory loss in Alzheimers disease (AD) is attributed to pervasive weakening and loss of synapses. Here, we present findings supporting a special role ......

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