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Human cyclophilin 40 unravels neurotoxic amyloids

Baker, JD; Shelton, LB; Zheng, DL; Favretto, F; Nordhues, BA; Darling, A; Sullivan, LE; Sun, ZY; Solanki, PK; Martin, MD; Suntharalingam, A; Sabbagh, JJ; Becker, S; Mandelkow, E; Uversky, VN; Zweckstetter, M; Dickey, CA; Koren, J; Blair, LJ

Blair, LJ (reprint author), Univ S Florida, Dept Mol Med, Tampa, FL 33620 USA.; Blair, LJ (reprint author), Univ S Florida, Byrd Alzheimers Inst, Tampa, FL 33620 USA.; Blair, LJ (reprint author), James A Haley Vet Hosp, Tampa, FL 33612 USA.

PLOS BIOLOGY, 2017; 15 (6):

Abstract

The accumulation of amyloidogenic proteins is a pathological hallmark of neurodegenerative disorders. The aberrant accumulation of the microtubule ass......

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