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Nanomolar Potency Aminophenyltriazine CFTR Activator Reverses Corneal Epithelial Injury in a Mouse Model of Dry Eye

Chen, XL; Lee, SJ; Zhang, TY; Duan, TY; Pasricha, ND; Schallhorn, JM; Levin, MH; Koprivica, V; Verkman, AS

Koprivica, V (corresponding author), Vanda Pharmaceut Inc, 2200 Penn Ave Northwest,Suite 300E, Washington, DC 20037 USA.; Verkman, AS (corresponding author), Univ Calif San Francisco, 1246 Hlth Sci East Tower,513 Parnassus Ave, San Francisco, CA 94143 USA.

JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS, 2020; 36 (3): 147

Abstract

Purpose: Dry eye disorders are a major health care burden. We previously reported the identification of N-methyl-N-phenyl-6-(2,2,3,3-tetrafluoropropox......

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