MeDIP combined with in-solution targeted enrichment followed by NGS: Inter-individual methylation variability of fetal-specific biomarkers and their implementation in a proof of concept study for NIPT-MedSci.cn

MeDIP combined with in-solution targeted enrichment followed by NGS: Inter-individual methylation variability of fetal-specific biomarkers and their implementation in a proof of concept study for NIPT

Keravnou, A; Ioannides, M; Loizides, C; Tsangaras, K; Achilleos, A; Mina, P; Kypri, E; Hadjidaniel, MD; Neofytou, M; Kyriacou, S; Sismani, C; Koumbaris, G; Patsalis, PC

Patsalis, PC (reprint author), Cyprus Inst Neurol & Genet, Translat Genet Team, Nicosia, Cyprus.; Patsalis, PC (reprint author), NIPD Genet Ltd, Nicosia, Cyprus.

PLOS ONE, 2018; 13 (6):

Abstract

DNA methylation is the most characterized epigenetic process exhibiting stochastic variation across different tissues and individuals. In non-invasive......

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MeDIP combined with in-solution targeted enrichment followed by NGS: Inter-individual methylation variability of fetal-specific biomarkers and their implementation in a proof of concept study for NIPT

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