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Heterogeneity, inherent and acquired drug resistance in patient-derived organoid models of primary liver cancer

Xian, LF; Zhao, P; Chen, X; Wei, ZM; Ji, HX; Zhao, J; Liu, WB; Li, ZS; Liu, DH; Han, X; Qian, YW; Dong, H; Zhou, X; Fan, JY; Zhu, XQ; Yin, JH; Tan, XJ; Jiang, DM; Yu, HP; Cao, GW

Cao, GW (通讯作者)，Second Mil Med Univ, Fac Navy Med, Dept Epidemiol, Shanghai 200433, Peoples R China.;Cao, GW (通讯作者)，Tongji Univ, Sch Med, Shanghai East Hosp, Key Lab Arrhythmias,Minist Educ, Shanghai 200120, Peoples R China.;Cao, GW (通讯作者)，Minist Educ, Key Lab Signaling Regulat & Targeting Therapy Liv, Shanghai 530022, Peoples R China.

CELLULAR ONCOLOGY, 2022; 45 (5): 1019

Abstract

Purpose We aimed to elucidate the applicability of tumor organoids for inherent drug resistance of primary liver cancer (PLC) and mechanisms of acquir......

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