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Silencing of Long Non-coding RNA GAS5 Suppresses Neuron Cell Apoptosis and Nerve Injury in Ischemic Stroke Through Inhibiting DNMT3B-Dependent MAP4K4 Methylation

Deng, YM; Chen, DD; Gao, F; Lv, H; Zhang, GJ; Sun, X; Liu, L; Mo, DP; Ma, N; Song, LG; Huo, XC; Yan, TY; Zhang, JB; Luo, Y; Miao, ZR

Miao, ZR (corresponding author), Capital Med Univ, Beijing Tiantan Hosp, Dept Intervent Neuroradiol, Beijing 100050, Peoples R China.; Miao, ZR (corresponding author), China Natl Clin Res Ctr Neurol Dis, Beijing 100070, Peoples R China.; Miao, ZR (corresponding author), Beijing Inst Brain Disorders, Ctr Stroke, Beijing 100069, Peoples R China.; Luo, Y (corresponding author), Nanjing Univ, Med Sch, Affiliated Drum Tower Hosp, Dept Neurol, Nanjing 210008, Peoples R China.

TRANSLATIONAL STROKE RESEARCH, 2020; 11 (5): 950

Abstract

Ischemic stroke is associated with various physiological and pathological processes including neuronal apoptosis. Growth-arrest-specific transcript 5 ......

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