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Transition-Metal-Free Reductive Hydroxymethylation of Isoquinolines

Reeves, BM; Hepburn, HB; Grozavu, A; Lindsay-Scott, PJ; Donohoe, TJ

Donohoe, TJ (reprint author), Univ Oxford, Dept Chem, Chem Res Lab, Mansfield Rd, Oxford OX1 3TA, England.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2019; 58 (44): 15697

Abstract

A transition-metal-free reductive hydroxymethylation reaction has been developed, enabling the preparation of tetrahydroisoquinolines bearing C4-quate......

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