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Molecular Fitness Landscapes from High-Coverage Sequence Profiling

Blanco, C; Janzen, E; Pressman, A; Saha, R; Chen, IA

Blanco, C (reprint author), Univ Calif Santa Barbara, Dept Chem & Biochem, Santa Barbara, CA 93106 USA.

ANNUAL REVIEW OF BIOPHYSICS, VOL 48, 2019; 48 (): 1

Abstract

The function of fitness (or molecular activity) in the space of all possible sequences is known as the fitness landscape. Evolution is a random walk o......

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