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Population Pharmacokinetic Modeling of Acetaminophen Protein Adducts in Adults and Children

Jiang, SB; Madrasi, K; Samant, T; Lagishetty, C; Vozmediano, V; Chiew, A; Abdel-Rahman, SM; James, LP; Schmidt, S

Schmidt, S (reprint author), Univ Florida, Dept Pharmaceut, Ctr Pharmacometr & Syst Pharmacol, Orlando, FL 32827 USA.

JOURNAL OF CLINICAL PHARMACOLOGY, 0; ():

Abstract

Acetaminophen protein adducts (adducts) are a well-established biomarker to diagnose acetaminophen toxicity. To date, the quantitative relationship be......

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