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Novel sarsasapogenin-triazolyl hybrids as potential anti-Alzheimer's agents: Design, synthesis and biological evaluation

Wang, WB; Wang, W; Yao, GD; Ren, Q; Wang, D; Wang, ZD; Liu, P; Gao, PY; Zhang, Y; Wang, SJ; Song, SJ

Zhang, Y; Song, SJ (reprint author), Shenyang Pharmaceut Univ, Dept Nat Prod Chem, Shenyang 110016, Liaoning, Peoples R China.; Wang, SJ (reprint author), Shenyang Pharmaceut Univ, Key Lab Struct Based Drug Design Discovery, Minist Educ, Shenyang 110016,

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018; 151 (): 351

Abstract

Sarsasapogenin, an active ingredient in Rhizoma anemarrhenae, is a promising bioactive lead compound in the treatment of Alzheimer's disease. To searc......

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