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NUDT15 genotype distributions in the Korean population

Kim, HT; Choi, R; Won, HH; Choe, YH; Kang, B; Lee, K; Koo, HH; Yoo, KH; Kim, YH; Lee, SY

Lee, SY (reprint author), Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Lab Med & Genet,Dept Clin Pharmacol & Therap, 81 Irwon Ro, Seoul 135710, South Korea.

PHARMACOGENETICS AND GENOMICS, 2017; 27 (5): 197

Abstract

Thiopurines have a narrow therapeutic range because of frequent toxicity (i.e. marrow suppression), which is only partly explained by TPMT genetic pol......

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