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A CDR-based approach to generate covalent inhibitory antibody for human rhinovirus protease

Cheng, YP; Wu, JY; Han, Y; Xu, JY; Da, Y; Zhao, Q; Guo, GY; Zhou, YN; Chen, YM; Liu, JH; Chen, HY; Jiang, XX; Cai, XQ

Cai, XQ (corresponding author), Sun Yat Sen Univ, Sch Pharmaceut Sci, 132 East Outer Ring Rd, Guangzhou 510006, Peoples R China.

BIOORGANIC & MEDICINAL CHEMISTRY, 2021; 42 ():

Abstract

Covalent target modulation with small molecules has been emerging as a promising strategy for drug discovery. However, covalent inhibitory antibody re......

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