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Study on production enhancement of validamycin A using online capacitance measurement coupled with H-1 NMR spectroscopy analysis in a plant-scale bioreactor

Zou, W; Wang, XH; Zhang, KP; Mohsin, A; Guo, MJ; Liu, HM; Zhang, L; Li, L; Zhang, SL; Zhuang, YP

Guo, MJ; Zhuang, YP (reprint author), East China Univ Sci & Technol, POB 329,130 Meilong Rd, Shanghai 200237, Peoples R China.

PROCESS BIOCHEMISTRY, 2018; 65 (): 28

Abstract

Herein, an improved production of validamycin A was obtained upon developing a fed-batch strategy in a plant scale bioreactor. The shift in metabolic ......

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