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Theoretical study of myriocin-binding mechanism targeting serine palmitoyltransferase

Yu, L; Jiang, YM; Xu, L; Jin, J; Pei, ZJ; Zhu, JY

Zhu, JY (通讯作者),Jiangnan Univ, Sch Pharmaceut Sci, Wuxi 214122, Jiangsu, Peoples R China.;Pei, ZJ (通讯作者),Nanjing Med Univ, Affiliated Wuxi Peoples Hosp 2, Wuxi 214001, Jiangsu, Peoples R China.

CHEMICAL BIOLOGY & DRUG DESIGN, 2022; 99 (3): 373

Abstract

Sphingolipids (SLs) are vital for cells as forming membrane and transducing signals. The first step for de novo biosynthesis of SLs is catalyzed by th......

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