HLA class I signal peptide polymorphism determines the level of CD94/NKG2-HLA-E-mediated regulation of effector cell responses-MedSci.cn

HLA class I signal peptide polymorphism determines the level of CD94/NKG2-HLA-E-mediated regulation of effector cell responses

Lin, ZS; Bashirova, AA; Viard, M; Garner, L; Quastel, M; Beiersdorfer, M; Kasprzak, WK; Akdag, M; Yuki, Y; Ojeda, P; Das, S; Andresson, T; Naranbhai, V; Horowitz, A; McMichael, AJ; Hoelzemer, A; Gillespie, GM; Garcia-Beltran, WF; Carrington, M

Carrington, M (通讯作者)，MIT & Harvard, Ragon Inst MGH, Cambridge, MA 02139 USA.;Carrington, M (通讯作者)，Frederick Natl Lab Canc Res, Basic Sci Program, Frederick, MD 21701 USA.;Carrington, M (通讯作者)，NCI, Lab Integrat Canc Immunol, Ctr Canc Res, Bethesda, MD 20892 USA.

Abstract

Human leukocyte antigen (HLA)-E binds epitopes derived from HLA-A, HLA-B, HLA-C and HLA-G signal peptides (SPs) and serves as a ligand for CD94/NKG2A ......

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HLA class I signal peptide polymorphism determines the level of CD94/NKG2-HLA-E-mediated regulation of effector cell responses

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