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Ischemia-Selective Cardioprotection by Malonate for Ischemia/Reperfusion Injury

Prag, HA; Aksentijevic, D; Dannhorn, A; Giles, AV; Mulvey, JF; Sauchanka, O; Du, LP; Bates, G; Reinhold, J; Kula-Alwar, D; Xu, ZL; Pellerin, L; Goodwin, RJA; Murphy, MP; Krieg, T

Murphy, MP; Krieg, T (通讯作者),Univ Cambridge, Dept Med, Cambridge CB2 0QQ, England.;Murphy, MP (通讯作者),Univ Cambridge, MRC Mitochondrial Biol Unit, Cambridge CB2 0XY, England.

CIRCULATION RESEARCH, 2022; 131 (6): 528

Abstract

Background: Inhibiting SDH (succinate dehydrogenase), with the competitive inhibitor malonate, has shown promise in ameliorating ischemia/reperfusion ......

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