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Unscheduled HDAC4 repressive activity in human fibroblasts triggers TP53-dependent senescence and favors cell transformation

Paluvai, H; Di Giorgio, E; Brancolini, C

Brancolini, C (reprint author), Univ Udine, Dept Med, Ple Kolbe 4, I-33100 Udine, Italy.

MOLECULAR ONCOLOGY, 2018; 12 (12): 2165

Abstract

Expression of the class IIa HDACs is frequently altered in different human cancers. In mouse models these transcriptional repressors can trigger trans......

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