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Ligand-bound glutamine binding protein assumes multiple metastable binding sites with different binding affinities

Zhang, L; Wu, SW; Feng, YT; Wang, D; Jia, XL; Liu, ZJ; Liu, JW; Wang, WN

Zhang, L (corresponding author), Chinese Acad Sci, Fujian Inst Res Struct Matter, State Key Lab Struct Chem, Fuzhou, Fujian, Peoples R China.; Wang, WN (corresponding author), Fudan Univ, Inst Biomed Sci, Dept Chem, Multiscale Res Inst Complex Syst, Shanghai, Peoples R China.

COMMUNICATIONS BIOLOGY, 2020; 3 (1):

Abstract

Protein dynamics plays key roles in ligand binding. However, the microscopic description of conformational dynamics-coupled ligand binding remains a c......

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