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Identification of gross deletions in FBN1 gene by MLPA

Yang, H; Ma, YY; Luo, MY; Zhao, K; Zhang, YH; Zhu, GY; Sun, XG; Luo, FY; Wang, L; Shu, C; Zhou, Z

Wang, L (reprint author), Cent S Univ, Xiangya Hosp, Dept Cardiovasc Surg, Changsha 410008, Hunan, Peoples R China.; Shu, C (reprint author), Chinese Acad Med Sci, Natl Ctr Cardiovasc Dis, Fuwai Hosp, State Key Lab Cardiovasc Dis,Ctr Vasc Surg, Beijing 10

HUMAN GENOMICS, 2018; 12 ():

Abstract

Background: Marfan syndrome (MFS) is an autosomal dominant connective tissue disorder caused by mutations in the FBN1 gene. Approximately 90% of class......

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