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Irinotecan and berberine co-delivery liposomes showed improved efficacy and reduced intestinal toxicity compared with Onivyde for pancreatic cancer

Wang, X; Liu, Y; Xu, WJ; Jia, LR; Chi, DX; Yu, J; Wang, JM; He, ZG; Liu, XH; Wang, YJ

Liu, XH (corresponding author), Shenyang Pharmaceut Univ, Sch Pharm, Dept Pharmaceut, Shenyang 110016, Liaoning, Peoples R China.; Wang, YJ (corresponding author), Shenyang Pharmaceut Univ, Wuya Coll Innovat, Shenyang 110016, Liaoning, Peoples R China.

DRUG DELIVERY AND TRANSLATIONAL RESEARCH, ; ():

Abstract

Onivyde is the first irinotecan (IRI) nanoliposome that could improve pharmacokinetics and tumor biodistribution of irinotecan. Although FDA approves ......

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