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CRISPR/Cas9-mediated targeted chromosome elimination

Zuo, EW; Huo, XN; Yao, X; Hu, XD; Sun, YD; Yin, JH; He, BB; Wang, X; Shi, LY; Ping, J; Wei, Y; Ying, WQ; Wei, W; Liu, WJ; Tang, C; Li, YX; Hu, JZ; Yang, H

Yang, H (reprint author), Chinese Acad Sci, CAS Ctr Excellence Brain Sci & Intelligence Techn, Inst Neurosci,Shanghai Inst Biol Sci, State Key Lab Neurosci,Key Lab Primate Neurobiol, Shanghai 200031, Peoples R China.; Hu, JZ (reprint author), Peking Univ,

GENOME BIOLOGY, 2017; 18 ( ):

Abstract

Background: The CRISPR/Cas9 system has become an efficient gene editing method for generating cells carrying precise gene mutations, including the rea......

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