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Biallelic TLR4 deficiency in humans

Capitani, M; Al-Shaibi, AA; Pandey, S; Gartner, L; Taylor, H; Hubrack, SZ; Agrebi, N; Al-Mohannadi, MJ; Al Kaabi, S; Vogl, T; Roth, J; Kotlarz, D; Klein, C; Charles, AK; Vijayakumar, V; Karim, MY; George, B; Travis, SP; Elawad, M; Lo, BRC; Uhlig, HH

Lo, BRC (通讯作者),Sidra Med, Translat Med Dept, Al Gharrafa St, Doha, Qatar.;Uhlig, HH (通讯作者),Univ Oxford, John Radcliffe Hosp, Translat Gastroenterol Unit, Headley Way, Oxford OX3 9DU, England.;Uhlig, HH (通讯作者),Univ Oxford, John Radcliffe Hosp, Dept Paediat, Headley Way, Oxford OX3 9DU, England.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2023; 151 (3): 783

Abstract

Background: Toll-like receptors (TLRs) mediate functions for host defense and inflammatory responses. TLR4 recognizes LPS, a component of gram-negativ......

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