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CRISPR/Cas9 treatment causes extended TP53-dependent cell cycle arrest in human cells

Geisinger, JM; Stearns, T

Stearns, T (corresponding author), Stanford Univ, Dept Biol, Stanford, CA 94305 USA.; Stearns, T (corresponding author), Stanford Univ, Dept Genet, Med Sch, Stanford, CA 94305 USA.

NUCLEIC ACIDS RESEARCH, 2020; 48 (16): 9067

Abstract

While the mechanism of CRISPR/Cas9 cleavage is understood, the basis for the large variation in mutant recovery for a given target sequence between ce......

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