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Disruption of RFX family transcription factors causes autism, attention-deficit/hyperactivity disorder, intellectual disability, and dysregulated behavior

Harris, HK; Nakayama, T; Lai, J; Zhao, BX; Argyrou, N; Gubbels, CS; Soucy, A; Genetti, CA; Suslovitch, V; Rodan, LH; Tiller, GE; Lesca, G; Gripp, KW; Asadollahi, R; Hamosh, A; Applegate, CD; Turnpenny, PD; Simon, MEH; Volker-Touw, CML; van Gassen, KLI; van Binsbergen, E; Pfundt, R; Gardeitchik, T; de Vries, BBA; Immken, LL; Buchanan, C; Willing, M; Toler, TL; Fassi, E; Baker, L; Vansenne, F; Wang, XD; Ambrus, JL; Fannemel, M; Posey, JE; Agolini, E; Novelli, A; Rauch, A; Boonsawat, P; Fagerberg, CR; Larsen, MJ; Kibaek, M; Labalme, A; Poisson, A; Payne, KK; Walsh, LE; Aldinger, KA; Balciuniene, J; Skraban, C; Gray, C; Murrell, J; Bupp, CP; Pascolini, G; Grammatico, P; Broly, M; Kury, S; Nizon, M; Rasool, IG; Zahoor, MY; Kraus, C; Reis, A; Iqbal, M; Uguen, K; Audebert-Bellanger, S; Ferec, C; Redon, S; Baker, J; Wu, YH; Zampino, G; Syrbe, S; Brosse, I; Jamra, RA; Dobyns, WB; Cohen, LL; Blomhoff, A; Mignot, C; Keren, B; Courtin, T; Agrawal, PB; Beggs, AH; Yu, TW

Yu, TW (corresponding author), Boston Childrens Hosp, Dept Pediat, Div Genet & Genom, Boston, MA 02115 USA.; Yu, TW (corresponding author), Harvard Med Sch, Boston, MA 02115 USA.; Yu, TW (corresponding author), Boston Childrens Hosp, Manton Ctr Orphan Dis Res, Boston, MA 02115 USA.; Yu, TW (corresponding author), Harvard Univ, Program Neurosci, Boston, MA 02115 USA.

GENETICS IN MEDICINE, ; ():

Abstract

Purpose We describe a novel neurobehavioral phenotype of autism spectrum disorder (ASD), intellectual disability, and/or attention-deficit/hyperactivi......

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