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Yes associated protein 1 promotes resistance to 5-fluorouracil in gastric cancer by regulating GLUT3-dependent glycometabolism reprogramming of tumor-associated macrophages

He, ZK; Chen, D; Wu, JN; Sui, CY; Deng, XQ; Zhang, PH; Chen, ZC; Liu, DK; Yu, J; Shi, JL; Li, GX; Yao, XX

Shi, JL; Li, GX; Yao, XX (corresponding author), Southern Med Univ, Nanfang Hosp, Sch Clin Med 1, Dept Gen Surg, Guangzhou, Guangdong, Peoples R China.; Shi, JL; Li, GX; Yao, XX (corresponding author), Southern Med Univ, Nanfang Hosp, Sch Clin Med 1, Guangdong Prov Key Lab Precis Med Gastrointestina, Guangzhou, Guangdong, Peoples R China.

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2021; 702 ():

Abstract

The antimetabolite 5-fluorouracil (5-FU) is a widely used chemotherapy regimen for the treatment of gastric cancer (GC). However, resistance to 5-FU r......

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