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Ca2+-dependent calmodulin binding to cardiac ryanodine receptor (RyR2) calmodulin-binding domains

Brohus, M; Sondergaard, MT; Chen, SRW; van Petegem, F; Overgaard, MT

Overgaard, MT (reprint author), Aalborg Univ, Dept Chem & Biosci, DK-9220 Aalborg, Denmark.

BIOCHEMICAL JOURNAL, 2019; 476 (): 193

Abstract

The Ca2+ sensor calmodulin (CaM) regulates cardiac ryanodine receptor (RyR2)-mediated Ca(2+)release from the sarcoplasmic reticulum. CaM inhibits RyR2......

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