Process validation, current good manufacturing practice production, dosimetry, and toxicity studies of the carbonic anhydrase IX imaging agent [In-111]In-XYIMSR-01 for phase I regulatory approval-MedSci.cn

Process validation, current good manufacturing practice production, dosimetry, and toxicity studies of the carbonic anhydrase IX imaging agent [In-111]In-XYIMSR-01 for phase I regulatory approval

De Silva, RA; Gorin, MA; Mease, RC; Minn, I; Lisok, A; Plyku, D; Nimmagadda, S; Allaf, ME; Yang, X; Sgouros, G; Rowe, SP; Pomper, MG

Pomper, MG (corresponding author), Johns Hopkins Univ, Sch Med, Russell H Morgan Dept Radiol & Radiol Sci, 601 North Caroline St, Baltimore, MD 21287 USA.

Abstract

[In-111]In-XYIMSR-01 is a promising single-photon emission computed tomography (SPECT) imaging agent for identification of tumors that overexpress car......

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Process validation, current good manufacturing practice production, dosimetry, and toxicity studies of the carbonic anhydrase IX imaging agent [In-111]In-XYIMSR-01 for phase I regulatory approval

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