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Identification and biological evaluation of novel benzothiazole derivatives bearing a pyridine-semicarbazone moiety as apoptosis inducers via activation of procaspase-3 to caspase-3

Ma, JJ; Ni, X; Gao, YL; Huang, K; Liu, JA; Wang, Y; Chen, RF; Wang, CF

Ma, JJ (reprint author), Huaqiao Univ, Sch Med, Quanzhou 362000, Peoples R China.; Wang, CF (reprint author), Quanzhou Normal Univ, Coll Oceanol & Food Sci, Quanzhou 362000, Peoples R China.

MEDCHEMCOMM, 2019; 10 (3): 465

Abstract

Three series of compounds were designed, synthesized and evaluated for their in vitro anticancer activity against a procaspase-3 over-expression cance......

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