Kir7.1 disease mutant T153I within the inner pore affects K+ conduction-MedSci.cn

Kir7.1 disease mutant T153I within the inner pore affects K+ conduction

Beverley, KM; Shahi, PK; Kabra, M; Zhao, QQ; Heyrman, J; Steffen, J; Pattnaik, BR

Pattnaik, BR (通讯作者)，Univ Wisconsin, Endocrinol & Reprod Physiol Grad Program, Sch Med & Publ Hlth, Madison, WI 53726 USA.;Pattnaik, BR (通讯作者)，Univ Wisconsin, Dept Pediat, Sch Med & Publ Hlth, Madison, WI 53726 USA.;Pattnaik, BR (通讯作者)，Univ Wisconsin, McPherson Eye Res Inst, Madison, WI 53726 USA.;Pattnaik, BR (通讯作者)，Univ Wisconsin, Dept Ophthalmol & Visual Sci, Sch Med & Publ Hlth, Madison, WI 53726 USA.

Abstract

Inward-rectifier potassium channel 7.1 (Kir7.1) is present in the polarized epithelium, including the retinal pigmented epithelium. A single amino aci......

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Kir7.1 disease mutant T153I within the inner pore affects K+ conduction

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