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Genomic insights into TASK-1 reveal functional roles in sleep apnea

Simonson, TS; Moya, EA; Malhotra, A

Malhotra, A (通讯作者),Univ Calif San Diego, Div Pulm Crit Care & Sleep Med, Dept Med, San Diego, CA 92093 USA.

NATURE GENETICS, 2022; 54 (10): 1451

Abstract

KCNK3 mutations identified in sleep apnea probands affect TASK-1 X-gate function. These changes lead to an increase in potassium current and open prob......

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