Frequent Emergence of Resistance Mutations Following Complex Intra-Host Genomic Dynamics in SARS-CoV-2 Patients Receiving Sotrovimab-MedSci.cn

Frequent Emergence of Resistance Mutations Following Complex Intra-Host Genomic Dynamics in SARS-CoV-2 Patients Receiving Sotrovimab

Palomino-Cabrera, R; Tejerina, F; Molero-Salinas, A; Ferris, M; Veintimilla, C; Catalan, P; Macias, GR; Alonso, R; Munoz, P; de Viedma, DG; Perez-Lago, L

de Viedma, DG; Perez-Lago, L (通讯作者)，Hosp Gen Univ Gregorio Maranon, Serv Microbiol Clin & Enfermedades Infecciosas, Madrid, Spain.;de Viedma, DG; Perez-Lago, L (通讯作者)，Inst Invest Sanitaria Gregorio Maranon IiSGM, Madrid, Spain.;de Viedma, DG (通讯作者)，Ctr Invest Biomed Red CIBER Enfermedades Respirato, Madrid, Spain.

Abstract

The emergence of the Omicron variant of SARS-CoV-2 represented a challenge to the treatment of COVID-19 using monoclonal antibodies. Only Sotrovimab m......

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Frequent Emergence of Resistance Mutations Following Complex Intra-Host Genomic Dynamics in SARS-CoV-2 Patients Receiving Sotrovimab

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