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Predicting base editing outcomes using position-specific sequence determinants

Pallaseni, A; Peets, EM; Koeppel, J; Weller, J; Vanderstichele, T; Ho, UL; Crepaldi, L; van Leeuwen, J; Allen, F; Parts, L

Parts, L (通讯作者),Wellcome Sanger Inst, Hinxton, England.;Parts, L (通讯作者),Univ Tartu, Dept Comp Sci, Tartu, Estonia.

NUCLEIC ACIDS RESEARCH, 2022; 50 (6): 3551

Abstract

CRISPR/Cas base editors promise nucleotide-level control over DNA sequences, but the determinants of their activity remain incompletely understood. We......

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