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The synergistic antitumor effect of IL-6 neutralization with NVP-BEZ235 in hepatocellular carcinoma

Wang, Y; Miao, XL; Jiang, YC; Wu, ZL; Zhu, XH; Liu, H; Wu, XY; Cai, JZ; Ding, XF; Gong, WH

Ding, XF (通讯作者),Zhejiang Sci Tech Univ, Coll Life Sci & Med, Hangzhou 310018, Zhejiang, Peoples R China.;Gong, WH (通讯作者),Zhejiang Univ, Affiliated Hosp 2, Sch Med, Dept Surg, Hangzhou 310058, Peoples R China.;Cai, JZ (通讯作者),Qingdao Univ, Affiliated Hosp, Organ Transplantat Ctr, Qingdao, Peoples R China.;Cai, JZ (通讯作者),Qingdao Univ, Affiliated Hosp, Liver Dis Ctr, Qingdao, Peoples R China.;Gong, WH (通讯作者),Zhejiang Univ, Med Ctr, Liangzhu Lab, Hangzhou 311121, Peoples R China.

CELL DEATH & DISEASE, 2022; 13 (2):

Abstract

Hepatocellular carcinoma (HCC) still ranks among the top cancers worldwide with high incidence and mortality. Due to abnormal activation of the PI3K/A......

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