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One-Pot Synthesis of Papaverine Hydrochloride and Identification of Impurities

Yu, WS; Wu, ZN; Qiu, ZF; Zhao, CJ; Zhang, FL; Yang, ZZ

Zhao, CJ (corresponding author), Shenyang Pharmaceut Univ, Sch Pharmaceut Engn, Shenyang 110016, Peoples R China.

RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2020; 56 (7): 1295

Abstract

A one-pot synthesis of papaverine hydrochloride with 99.6% purity was performed using xylene as solvent for the entire process. The critical parameter......

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