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Raloxifene inhibits the overexpression of TGF-beta 1 in cartilage and regulates the metabolism of subchondral bone in rats with osteoporotic osteoarthritis

Ping, SH; Tian, FM; Liu, H; Sun, Q; Shao, LT; Lian, QQ; Zhang, L

Zhang, L (corresponding author), Hebei Med Univ, Dept Orthoped Surg, 361 Zhongshan East Rd, Shijiazhuang 050017, Hebei, Peoples R China.

BOSNIAN JOURNAL OF BASIC MEDICAL SCIENCES, 2021; 21 (3): 284

Abstract

Overexpression of transforming growth factor-beta 1 (TGF-beta 1) and subchondral bone remodeling play key roles in osteoarthritis (OA). Raloxifene (RA......

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