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Inferring mammalian tissue-specific regulatory conservation by predicting tissue-specific differences in open chromatin

Kaplow, IM; Schaffer, DE; Wirthlin, ME; Lawler, AJ; Brown, AR; Kleyman, M; Pfenning, AR

Kaplow, IM; Pfenning, AR (通讯作者),Carnegie Mellon Univ, Dept Computat Biol, Pittsburgh, PA 15213 USA.;Kaplow, IM; Pfenning, AR (通讯作者),Carnegie Mellon Univ, Neurosci Inst, Pittsburgh, PA 15213 USA.;Pfenning, AR (通讯作者),Carnegie Mellon Univ, Dept Biol, Pittsburgh, PA 15213 USA.

BMC GENOMICS, 2022; 23 (1):

Abstract

Background Evolutionary conservation is an invaluable tool for inferring functional significance in the genome, including regions that are crucial acr......

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