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Determination of Total and Unbound Meropenem, Imipenem/Cilastatin, and Cefoperazone/Sulbactam in Human Plasma: Application for Therapeutic Drug Monitoring in Critically Ill Patients

Rao, Z; Dang, ZL; Li, B; Zhu, L; Qin, HY; Wu, XA; Wei, YH

Wei, YH (corresponding author), Lanzhou Univ, Dept Pharm, Hosp 1, Lanzhou 730000, Peoples R China.

THERAPEUTIC DRUG MONITORING, 2020; 42 (4): 578

Abstract

Background: Critically ill patients show several pathophysiological alterations that can complicate antibiotic dosing. Hence, there is a strong ration......

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