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Design, synthesis, and biological evaluation of 5-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)-1H-Indole-2-Carbohydrazide derivatives: the methuosis inducer 12A as a Novel and selective anticancer agent

Wu, J; Hu, HY; Ao, MT; Cui, ZZ; Zhou, XP; Qin, JB; Guo, YF; Chen, JW; Xue, YH; Fang, MJ

Chen, JW; Xue, YH; Fang, MJ (corresponding author), Xiamen Univ, Sch Pharmaceut Sci, South Xiang An Rd, Xiamen 361102, Peoples R China.; Chen, JW; Xue, YH; Fang, MJ (corresponding author), Xiamen Univ, Sch Publ Hlth, South Xiang An Rd, Xiamen 361102, Peoples R China.

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2021; 36 (1): 1436

Abstract

This study describes the synthesis and vacuole-inducing activity of 5-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)-1H-indole-2-carbohydrazide derivatives, ......

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