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Combining probabilistic alignments with read pair information improves accuracy of split-alignments

Shrestha, AMS; Yoshikawa, N; Asai, K

Shrestha, AMS (reprint author), Univ Tokyo, Grad Sch Frontier Sci, Dept Computat Biol & Med Sci, 5-1-5 Kashiwanoha, Kashiwa, Chiba, Japan.

BIOINFORMATICS, 2018; 34 (21): 3631

Abstract

Motivation: Split-alignments provide base-pair-resolution evidence of genomic rearrangements. In practice, they are found by first computing high-scor......

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