Suppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels-MedSci.cn

Suppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels

Chen, X; Li, JQ; Zhang, R; Zhang, Y; Wang, XX; Leung, ELH; Ma, LJ; Wong, VKW; Liu, L; Neher, E; Yu, HJ

Wong, VKW; Liu, L; Neher, E; Yu, HJ (通讯作者)，Macau Univ Sci & Technol, Dr Nehers Biophys Lab Innovat Drug Discovery, State Key Lab Qual Res Chinese Med, Taipa, Macau, Peoples R China.;Neher, E (通讯作者)，Max Planck Inst Multidisciplinary Sci, Emeritus Lab Membrane Biophys, D-37077 Gottingen, Germany.;Liu, L (通讯作者)，Macau Univ Sci & Technolgy, State Key Lab Qual Res Chinese Med, Ave Wai Long, Taipa, Macau, Peoples R China.;Liu, L (通讯作者)，Guangzhou Univ Chinese Med, Affiliated Hosp 2, State Key Lab Dampne

Abstract

Blockade of immune checkpoints as a strategy of cancer cells to overcome the immune response has received ample attention in cancer research recently.......

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Suppression of PD-L1 release from small extracellular vesicles promotes systemic anti-tumor immunity by targeting ORAI1 calcium channels

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