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KDM5B demethylates H3K4 to recruit XRCC1 and promote chemoresistance

Xu, WX; Zhou, BL; Zhao, XY; Zhu, LY; Xu, JY; Jiang, ZN; Chen, DW; Wei, Q; Han, MJ; Feng, LF; Wang, SY; Wang, X; Zhou, JW; Jin, HC

Jin, HC (reprint author), Zhejiang Univ, Med Sch, Sir Run Run Shaw Hosp, Key Lab Biotherapy Zhejiang,Lab Canc Biol, Hangzhou, Zhejiang, Peoples R China.

INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2018; 14 (9): 1122

Abstract

Chemotherapy is the main treatment for human cancers including gastric cancer. However, in response to chemotherapeutic drugs, tumor cells can develop......

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