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Systematic Evaluation of Mycobacterium tuberculosis Proteins for Antigenic Properties Identifies Rv1485 and Rv1705c as Potential Protective Subunit Vaccine Candidates

Wang, YG; Li, ZH; Wu, SC; Fleming, J; Li, CY; Zhu, GF; Chen, B; Ren, BG; Wang, XY; Du, BP; Li, PJ; Hu, PL; Yang, JW; Liu, Y; Zhou, CC; Zhang, XE; Bi, LJ; Zhang, HT; Yang, JM; Zhang, ZD

Zhang, HT (corresponding author), Chinese Acad Sci, CAS Ctr Excellence Biomacromol, Inst Biophys, Key Lab RNA Biol, Beijing, Peoples R China.; Zhang, ZD (corresponding author), Capital Med Univ, Beijing Chest Hosp, Beijing TB & Thorac Tumor Res Inst, Beijing Key Lab Drug Resistant TB Res, Beijing, Peoples R China.; Yang, JM (corresponding author), Zhengzhou Univ, Childrens Hosp, Zhengzhou, Henan, Peoples R China.

INFECTION AND IMMUNITY, 2021; 89 (3):

Abstract

The lack of efficacious vaccines against Mycobacterium tuberculosis (MTB) infection is a limiting factor in the prevention and control of tuberculosis......

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