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Novel multi-target ligands of dopamine and serotonin receptors for the treatment of schizophrenia based on indazole and piperazine scaffolds-synthesis, biological activity, and structural evaluation

Stepnicki, P; Wronikowska-Denysiuk, O; Zieba, A; Targowska-Duda, KM; Bartyzel, A; Wróbel, MZ; Wróbel, TM; Szalaj, K; Chodkowski, A; Mirecka, K; Budzynska, B; Fornal, E; Turlo, J; Castro, M; Kaczor, AA

Stepnicki, P; Kaczor, AA (通讯作者),Med Univ Lublin, Fac Pharm, Dept Synth & Chem Technol Pharmaceut Subst, Lublin, Poland.

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2023; 38 (1):

Abstract

Schizophrenia is a chronic mental disorder that is not satisfactorily treated with available antipsychotics. The presented study focuses on the search......

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